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From Interstate-10:
Exit Tallahassee at 192 (toward FAMU and FSU). Travel 7 miles into town on Hwy 90/Mahan/Tennessee Street. Make a LEFT at MERIDIAN, just past Leon High School. Travel 5 blocks to Jefferson Street and make a RIGHT and a quick LEFT into the parking lot.

Traveling from North Monroe Street:
Make a LEFT onto TENNESSEE STREET. Make a RIGHT onto CALHOUN STREET. Travel for about five blocks and make a LEFT onto JEFFERSON STREET, next to the Bank of America building, behind the Leon County Courthouse. The museum is two blocks on the RIGHT.

Traveling from South Monroe Street:
Make a RIGHT turn onto GAINES STREET, traveling east. Make a LEFT onto GADSDEN STREET, a one-way street heading north. Make a RIGHT onto JEFFERSON STREET. The museum on the second block on the RIGHT.

From Apalachee Parkway (traveling west towards the Capitol):
Exit at the FRANKLIN BLVD/GADSDEN STREET off-ramp. Cross FRANKLIN BLVD, keeping straight through the light. Make a RIGHT on MERIDIAN. The museum is on the LEFT.